Manoj K. Bhasin: Spatial architecture and cellular landscape of the medulloblastoma

Manoj K. Bhasin, Co-Founder and Chief Scientific Advisor at Canomiks, shared on LinkedIn:

“We’re thrilled to share the preprint of our article titled, “Medulloblastoma Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity with High-Density Progenitor Cell Regions Correlating with High-Risk Disease” at bioRxiv.

Thanks to our dedicated team members and collaborators MacDonald Tobey for making this possible. Big thanks to Franklin Chien, and Marina Michaud for leading the effort and performing excellent analysis.

This is the first story mapping spatial architecture and cellular landscape of the medulloblastoma (MB) TME and identifying dense regions of quiescent progenitor-like MB cells enriched in patients with high-risk (HR) features.

Read Full Article here.”

Source: Manoj K. Bhasin/LinkedIn

Medulloblastoma Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity with High-Density Progenitor Cell Regions Correlating with High-Risk Disease

Authors: Franklin Chien, Marina E. Michaud, Mojtaba Bakhtiari, Chanel Schroff, Matija Snuderl, Jose E. Velazquez Vega, Tobey J. MacDonald, Manoj K. Bhasin