November, 2024
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Tom Powles: First-Line UC Trials – Ipi/Nivo Fails on OS, Durva/Treme Shows Potential in PD-L1 Positive Patients
Nov 5, 2024, 17:40

Tom Powles: First-Line UC Trials – Ipi/Nivo Fails on OS, Durva/Treme Shows Potential in PD-L1 Positive Patients

Tom Powles, Director of Barts Cancer Centre, shared a post on X:

“Just out. Ipi/nivo didn’t hit OS in cisplatin ineligible or PD-L1 +ve in 1st line UC in CM901.

Surprising? Durva/treme (also -ve) had activity, especially in PD-L1 +ves (HR 0.74, CI 0.6-0.9-not stat tested). Different PD-L1 biomarkers used.

Data awaited.”

Tom Powles: First-Line UC Trials - Ipi/Nivo Fails on OS, Durva/Treme Shows Potential in PD-L1 Positive Patients

Read further.

More posts featuring Tom Powles.

Professor Thomas Powles, specializing in urology cancer, holds the position of Professor at the University of London since 2012 and serves as the Director of Barts Cancer Centre, a CRUK Major Cancer Centre.

With a role in biomarker development and drug strategies, he has secured multiple EMA and FDA approvals. His achievements include advancing front-line immune/targeted therapy combinations in RCC and immune checkpoint inhibition in bladder cancer.