![Michael O’Dwyer: Nice paper from group of Simon Wisnovsky shedding more light on nature of Siglec-7 ligands](https://oncodaily.com/pub/uploads/2024/01/IMG_1350.jpeg)
A collage photo of Michael O'Dwyer, Simon Wisnovsky, John Daly and Carolyn Bertozzi
Jan 12, 2024, 17:22
Michael O’Dwyer: Nice paper from group of Simon Wisnovsky shedding more light on nature of Siglec-7 ligands
Michael O’Dwyer,
at Saolta University Health Care Group, shared on LinkedIn:“Nice paper from group of Simon Wisnovsky, including my former PhD student John Daly along with Carolyn Bertozzi shedding more light on nature of Siglec-7 ligands! Seem to be predominantly disialyl core 1 O-glycans and are highly expressed on naive T cells and play an important role in regulation of T cell activation. Of course these ligands on tumor cells (or stromal, yes stromal cells!) can inhibit immune cell function too in setting of cancer.”
Source: Michael O’Dwyer/LinkedIn