10 papers suggested by Wafik S. El-Deiry

Wafik S. El-Deiry, Director of the Legorreta Cancer Center of Brown University and Associate Dean for Oncologic Sciences at the Warren Alpert Medical School, shared a few must-reads papers on X:

1. Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium

Authors: Kaixin Liang, Katherine C. Barnett, Martin Hsu, Wei-Chun Chou, Sachendra S. Bais, Kristina Riebe, Yuying Xie, Tuong Thien Nguyen, Thomas H. Oguin III, Kevin M. Vannella, Stephen M. Hewitt, Daniel S. Chertow, Maria Blasi, Gregory D. Sempowski, Amelia Karlsson, Beverly H. Koller, Deborah J. Lenschow, Scott H. Randell, and Jenny P.-Y. Ting.

2. CD5 deletion enhances the antitumor activity of adoptive T cell therapies

Authors: Ruchi P. Patel, Guido Ghilardi, Yunlin Zhang, Yi-Hao Chiang, Wei Xie, Puneeth Guruprasad, Ki Hyun Kim, Inkook Chun, Mathew G. Angelos, and Marco Ruella.

3. Reprogramming human B cells with custom heavy-chain antibodies

Authors: Geoffrey L. Rogers, Chun Huang, Atishay Mathur, Xiaoli Huang, Hsu-Yu Chen, Kalya Stanten, Heidy Morales, Chan-Hua Chang, Eric J. Kezirian, and Paula M. Cannon.

4. Proteomic signatures improve risk prediction for common and rare diseases

Authors: Julia Carrasco-Zanini, Maik Pietzner, Jonathan Davitte, Praveen Surendran, Damien C. Croteau-Chonka, Chloe Robins, Ana Torralbo, Christopher Tomlinson, Florian Grünschläger, Natalie Fitzpatrick, Cai Ytsma, Tokuwa Kanno, Stephan Gade, Daniel Freitag, Frederik Ziebell, Simon Haas, Spiros Denaxas, Joanna C. Betts, Nicholas J. Wareham, Harry Hemingway, Robert A. Scott, and Claudia Langenberg.

5. New law requires state health plans in Florida to cover biomarker testing

Authors: Stephanie Colombini.

6. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Authors: Anissa A. Widjaja, Wei-Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh K. Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L. George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A. Sims, Norbert Hübner, Enrico Petretto, Dominic J. Withers, Lena Ho, Jesus Gil, Stuart A. Cook et al.

7. Mice live longer when inflammation-boosting protein is blocked

Authors: Heidi Ledford.

8. Alzheimer Disease and Related Dementia Following Hormone-Modulating Therapy in Patients With Breast Cancer

Authors: Chao Cai, Kaowao Strickland, Sophia Knudsen et al.

9. Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution

Authors: Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert E. Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan and Nnennaya Kanu.

10. In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution

Authors: Peter F. Renz, Umesh Ghoshdastider, Simona Baghai Sain, Fabiola Valdivia-Francia, Ameya Khandekar, Mark Ormiston, Martino Bernasconi, Clara Duré, Jonas A. Kretz, Minkyoung Lee, Katie Hyams, Merima Forny, Marcel Pohly, Xenia Ficht, Stephanie J. Ellis, Andreas E. Moor and Ataman Sendoel.

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Wafik El-Deiry, MD, PhD, FACP, FRSM, is the Associate Dean for Oncologic Sciences at the Warren Alpert Medical School and Director of the Legorreta Cancer Center of Brown University and Director of the Joint Program in Cancer Biology at Brown University and affiliated hospitals.

Dr. El-Deiry discovered p21(WAF1) as a p53 target gene, cell cycle inhibitor, and tumor suppressor that explained the mammalian cell stress response. Dr. El-Deiry’s research is focused on mechanisms of therapy resistance with major efforts in drug discovery and development.