Gustavo Viani: Prophylactic Pelvic RT with SBRT for High-Risk node negative Prostate Cancer
Gustavo Viani, Professor of Radiation Oncology at Ribeirão Preto Medical School, shared a recent article by Vedang Murthy and colleagues on X:
“Breaking: Prophylactic Pelvic RT with SBRT for High-Risk node negative Prostate Cancer.
New results from the SHARP consortium show that 25 Gy /5 fractions achieve 98.2% pelvic control, offering a groundbreaking approach to regional control in high-risk, node-negative prostate cancer.
Methods:
Pooled analysis of 171 people treated across Multi-center data from the U.S., Canada, and India under the SHARP consortium.
Regimen:
- Prostate SBRT (35–40 Gy/5fr ) + Pelvic RT (25 Gy/5 fraction).
- Delivered with IGRT (CB CT).
Key Outcomes:
- Median FU 51 months.
- 5-Year BFFS: 86.1%.
- 5-Year OS: 89.3%
- Only 1.8% pelvic recurrence all with distant mets.
Clinical implications:
This regimen is effective, safe, and supports the growing adoption of ultra-hypo for high-risk. It is efficiency with strong clinical outcomes.
Are you using SBRT with this approach?
Share your experiences below.”
Authors: Vedang Murthy, Indranil Mallick, Priyamvada Maitre, Gargee Mulye, Moses Arunsingh, Luca Valle, Michael Steinberg, Thomas Kennedy, Andrew Loblaw and Amar U Kishan
Gustavo Viani, MD is an Associate Professor in the Department of Medical Imaging, Hematology, and Oncology at Hospital das Clínicas, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP). Dr. Viani’s research focuses on radiation oncology, with expertise in brachytherapy, stereotactic radiosurgery, dose fractionation, radiation tolerance, and overall oncology practices.
More posts featuring Gustavo Viani.
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ASCO Annual Meeting
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OncoThon 2024, Online
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Global Summit on War & Cancer 2023, Online
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