Gabe Sonke: Grateful to all patients who participated in the SONIA trial
Gabe Sonke, Professor of Clinical Oncology at the Netherlands Cancer Institute, shared a post by The Netherlands Cancer Institute, on LinkedIn:
“Very grateful to all patients who participated in the SONIA trial and proud of the study team and all participating sites.
These results can help to reduce toxicities of CDK4/6 inhibitors in advanced breast cancer and reduce the treatment burden on patients and health care systems.”
Quoting The Netherlands Cancer Institute’s post:
“First results of the SONIA trial are now published in Nature.
The prestigious journal Nature published the initial results of the SONIA study today.
The study showed that delaying and shortening the duration of treatment with CDK4/6 inhibitors for patients with hormone receptor-positive advanced breast cancer, leads to similar survival outcomes while reducing toxicity and achieving substantial cost savings.
This is the first time an efficiency study like this has been conducted in collaboration with Dutch health insurance providers and the Ministry of Heath, and it highlights the importance of research into the efficient use of medicines for patients, physicians, and policymakers worldwide.
Today’s publication in Nature underlines the potential of this type of self-funded efficiency research. The SONIA results reaffirm the need for robust sequencing trial data to determine the optimal use of our available therapies.
But most importantly, this type of mostly post-marketing academic research can be of great benefit to patients and society, and should be conducted more frequently.
We are very proud to have conducted this study within the Dutch Breast Cancer Cancer Research Group (BOOG Study Center) and in collaboration with the Dutch Breast Cancer Society (BVN), the Netherlands Comprehensive Cancer Organisation (IKNL (Integraal Kankercentrum Nederland) and the institute for Medical Technology Assessment (iMTA).
We want to thank all the patients who have participated in the trial, as well as the study staff throughout all 74 participating hospitals.
We extend a special appreciation to the principal investigators Agnes Jager, Gabe Sonke and Inge Konings, and their PhD students Annemiek van Ommen – Nijhof and Noor Wortelboer.
Last, the study team wants to thank the Netherlands Organization for Health Research (ZonMw) and Development and Dutch Health Insurers (ZN) for funding this trial.”
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