Robert Orlowski, Director of Myeloma Section at MD Anderson Cancer Center, shared on X:

“Myeloma Paper of the Day: Combining surface proteomics with computational approaches to design NOT gated CAR T-cells that are down-regulated when an inhibitory CAR is bound by a normal tissue antigen to expand the target repertoire in myeloma.”

Targeting myeloma essential genes using NOT Gated CAR T-cells, a computational approach

Authors: Ieuan G. Walker, James P. Roy, Georgina S. F. Anderson, Jose Guerrero Lopez, and Michael A. Chapman.

Source: Robert Orlowski/X