Sanam Loghavi: The most picturesque/textbook example of AITL you will see in 2024
Sanam Loghavi posted on X/Twitter:
“The most picturesque/textbook example of AITL you will see in 2024… What the WHO 5th now refers to as ‘Nodal T follicular helper cell lymphoma, angioimmunoblastic type’
why is that.. you may ask??
Allow me to tell you why.
Nodal TFH lymphoma angioimmunoblstic type (AITL) has 3 histologic patterns. This one is combination of patterns 2 and 3 (It’s common to see more than one pattern in one lymph node).
The morphology is characterized by a triad of
1. Polymorphous cell infiltrate (plasma cells, histiocyte, eosinophils and the clear neoplastic T cells)
2. Follicular dendritic cell hyperplasia
3. High endothelial venule proliferation
There you have it…. A perfect AITL on one slide.”
Source: Sanam Loghavi/X
Sanam Loghavi is an Associate Professor of Pathology and Laboratory Medicine at the Department of Hematopathology at MD Anderson Cancer Center. She is the Medical Director of the ECOG/ACRIN Leukemia Bank at the Central Biorepository and Pathology Facility at MD Anderson.
She has authored around 200 peer-reviewed publications focused on hematologic neoplasms and is a co-investigator on several national and internationally-run clinical trials for hematologic malignancies. She serves on various committees including the HPATH Committee of the College of American Pathologists and the Education and Outreach Committees for International Clinical Cytometry Society.
