Manni Mohyuddin: It is often well known that the control arm is inferior prior to a single patient being enrolled on trial!

Manni Mohyuddin, Assistant Professor at the Huntsman Cancer Institute, University of Utah, shared on X/Twitter:

“A common excuse for poor control arms is that they were valid at the time the trial enrolled. We have shown in The Lancet Haematology, that it is often well known that the control arm is inferior prior to a single patient being enrolled on trial!”

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Source: Manni Mohyuddin/X