Erman Akkus: Hormone replacement therapy and colorectal cancer

Erman Akkus, Medical Oncologist at Ankara University, shared on X:

“Hormone replacement therapy (estrogen plus progestin) and colorectal cancer WHI trial 24-year results

-No influence on CRC incidence
-No difference in CRC deaths

No clinically meaningful benefit (in contrast to fewer CRC reported in the first 5-year results).”

Estrogen Plus Progestin and Colorectal Cancer: Long-Term Findings From the Women’s Health Initiative Randomized Clinical Trial published in JCO

Authors: Rowan T. Chlebowski, Aaron K. Aragaki, Kathy Pan, Juhua Luo, Thomas E. Rohan, Karen C. Johnson, Jean Wactawski-Wende, Su Yon Jung, Qian Xiao, JoAnn E. Manson, and Michael S. Simon.

Source: Erman Akkus/X