Pancreatic adenocarcinoma to develop unique mitochondrial subpopulations under stress
Yan Leyfman, Co-founder and Executive Director of MedNews Week, shared following post on LinkedIn:
”Study from Memorial Sloan Kettering Cancer Center led by Craig Thompson reveals that pancreatic adenocarcinoma develops unique mitochondrial subpopulations under stress, potentially driving cancer progression.
This adaptation is not seen in normal tissue, offering new insights into cancer metabolism and paving the way for targeted therapies.”
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
Authors: Keun Woo Ryu, Tak Shun Fung, Daphne C. Baker, Michelle Saoi, Jinsung Park, Christopher A. Febres-Aldana, Rania G. Aly, Ruobing Cui, Anurag Sharma, Yi Fu, Olivia L. Jones, Xin Cai, H. Amalia Pasolli, Justin R. Cross, Charles M. Rudin, Craig B. Thompson.
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