Aaron Goodman: Platelet Function Studies Made Simple
Aaron Goodman, Associate Professor of Medicine at the University of California, shared a post on X:
“Platelet Function Studies Made Simple – a must know for heme board!
Platelets agonist (ADP) added.
Platelets aggregate (clump).
Decrease light absorbed by platelet clump.
Decrease light passes->detected by photocell.
Bernard Soulie-
Gp1bV-IX Plt bind VWF
Platelets clump to all agonist but ristocetin.
Glanzman GPIIbIIIa
Pltclump to all agonist
Remember GPIIbIIIa binds fibrin and forms bridges between plt
No GPIIbIIIa then know bridge and no matter what Platelets won’t clump.”
Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.
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