Photo of Erman Akkus taken from mn.uio.no
Apr 16, 2024, 10:57
Erman Akkus: 2 studies from JAMA and Thyroid Journal
Erman Akkus, Medical Oncology Fellow at Ankara University, shared on X/Twitter:
1.” Second primary breast cancer among young (≤40 yr) stage 0-III breast cancer survivors: a study of JAMA.
At median 10 years:
- 2.2% for women who did not carry a germline pathogenic variant;
- 8.9% for carriers of a pathogenic variant;
- PV (pathogenic variant) carriers vs non carriers sHR (sub-hazard ratio): 5.27( 1.43-19.43).
Importance of germ line genetic testing in young women with breast cancer!”
Source: Erman Akkus/X
2. ”Pembrolizumabin addition to Dabrafenib/Trametinib for BRAFV600E-mutated anaplastic thyroid carcinoma: a study by Thyroid Journal.
Pembrolizumab added upfront or at progression vs dabra-trame alone:
- mOS: 17 vs 9 mo, p=0.03
- mPFS: 11 vs 4 mo, p=0.04
If dabra-trame given as neoadjuvant (before surgery), mOS: 63 mo.”
Source: Erman Akkus/X
Jul 27, 2024, 10:29