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Jul 31, 2023, 08:08
Thrombocytopenia all you need to know – Aaron Goodman
Thrombocytopenia all you need to know!
3 mechanisms
1. Decreased production = Marrow disorder = decreased megakaryocytes
Liver disease = decreased TPO production
2. Destruction/consumption = Immune-mediated (ITP), Non-immune (TMA, drugs)
3. Sequestration = Splenomegaly
Pseudo (platelet clump due to EDTA)
