Stephen V Liu: Need more data on PKs with crushing TKI pills

Stephen V Liu, Director of Thoracic Oncology and Developmental Therapeutics at Lombardi Comprehensive Cancer Center, posted on X/Twitter:

“Case report Clinical Lung Cancer on crushed dabrafenib + trametinib via NG tube in patient with BRAF V600E NSCLC, intubated in ICU. Patient received treatment via NGT for 33d, responded, was extubated, PFS ~6m. Need more data on PKs with crushing TKI pills!”

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Source: Stephen V Liu/X