May community eradication of Helicobacter pylori prevent gastric cancer?

Erman Akkus, Medical Oncologist at Ankara University, shared on X:

“May community eradication of Helicobacter pylori prevent gastric cancer?

• 102.330 patients with positive urea breath test radomized to eradication or symptomatic treatment
  
• 11.8 year follow-up
  
• Incidence HR: 0.86, 95% CI (0.74–0.99), p=0.04
  
• Reduced incidence and mortality in <45 yo

‘Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial‘

Authors: Kai-Feng Pan, Wen-Qing Li, Lian Zhang, Wei-Dong Liu, Jun-Ling Ma, Yang Zhang, Kurt Ulm, Jian-Xi Wang, Lei Zhang, Monther Bajbouj, Lan-Fu Zhang, Ming Li, Michael Vieth, Michael Quante, Le-Hua Wang, Stepan Suchanek, Raquel Mejías-Luque, Heng-Min Xu, Xiao-Han Fan, Xuan Han, Zong-Chao Liu, Tong Zhou, Wei-Xiang Guan, Roland M. Schmid, Markus Gerhard, Meinhard Classen, Wei-Cheng You.”

Source: Erman Akkus/X