Michiel van der Heijden: Explaining inconsistent results in urothelial cancer with chemo plus IO

Michiel van der Heijden, Medical Oncologist at Netherlands Cancer Institute, shared on X:

“Results of chemo plus IO have produced inconsistent results in urothelial cancer. Opposing effects of pro- and anti-inflammatory changes may explain some of this.”

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Source: Michiel van der Heijden/X

Authors: Maksim A. Chelushkin, Jeroen van Dorp, Sandra van Wilpe, Iris M. Seignette, Jan-Jaap J. Mellema, Maartje Alkemade, Alberto Gil-Jimenez, Dennis Peters, Wim Brugman, Chantal F. Stockem, Erik Hooijberg, Annegien Broeks, Bas W.G. van Rhijn, Laura S. Mertens, Antoine G. Van der Heijden, Niven Mehra, Maurits L. van Montfoort, Lodewyk F.A. Wessels, Daniel J. Vis, Michiel S. Van der Heijden

Platinum-based chemotherapy induces opposing effects on immunotherapy response-related spatial and stromal biomarkers in the bladder cancer microenvironment