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Thor Halfdanarson: Need info on the rare acinar cell carcinoma of the pancreas?
Jan 9, 2025, 14:23

Thor Halfdanarson: Need info on the rare acinar cell carcinoma of the pancreas?

Thor Halfdanarson, Vice President of the North American Neuroendocrine Tumor Society, shared a recent article by Zishuo Ian Hu et al, on X, adding:

“Need info on the rare acinar cell carcinoma of the pancreas (PACC)?

48% with resectable tumors and 5-year Overall Survival following resection was 72%.

Outcomes of patients with metastatic and unresectable PACC are poor, 5-year Overall Survival of 21 percent, seemingly better than PDAC.”

Molecular Profiling of Biliary Tract Cancers in African American and Caucasian Patients

Authors: Zishuo Ian Hu, Dean C. Pavlick, Jeffrey S. Ross, Sunyoung S. Lee, Madhulika Eluri, Milind Javle.

Thor Halfdanarson: Need info on the rare acinar cell carcinoma of the pancreas?

Thor Halfdanarson: Need info on the rare acinar cell carcinoma of the pancreas?

“The majority were pure PACC but 17 percent PACC/NEC.

Objective Response Rate 73 percent with chemo + RT in localized disease.

Progression-free survival and Overall Survival 108 and 27.3 mos in metastatic disease on FOLFIRINOX.

Molecular alterations common, most commonly HRD, both somatic and germline.”

Thor Halfdanarson: Need info on the rare acinar cell carcinoma of the pancreas?

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