Rahul Banerjee: IL-18: magnifying glass, rejuvenating cream, and phone-a-friend all in one for T cells

Rahul Banerjee, Assistant Professor at UW Medicine, shared a post on X:

”Fascinating MMsm work in Blood Journal by van den Brink Lab! IL-18-armored CAR-T cells overcome low target expression + better response, inc. IFNγ –> macrophages. IL-18: magnifying glass, rejuvenating cream, and phone-a-friend all in one for T cells?

IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model

Author: Brandon D. Ng, Adhithi Rajagopalan, Anastasia I. Kousa, Jacob S. Fischman, Sophia Chen, Alyssa Massa, Harold K. Elias, Dylan Manuele, Michael Galiano, Andri L. Lemarquis, Alexander P. Boardman, Susan DeWolf, Jonah Pierce, Bjarne Bogen, Scott E. James, Marcel R. M. van den Brink.”

Source: Rahul Banerjee/X