Vivek Subbiah: How to build a successful phase 1 program?

Vivek Subbiah posted the following on X/Twitter:

“How to build a successful phase 1 program?

– Phase I physicians should be those who are ready to see patients across the malignancy spectrum.
– Faculty and staff for an early-phase unit should be fully focused on this work, and not doing it as a “side hobby.”
– Patients should be prescreened before the clinic for protocol eligibility, and the basic principle of the patient comes first must be followed—hence coordinators should wait for the patients, not vice versa.
– Finally, for phase, I unit leaders and team members, education must be an iterative process for their lifetime with the unit, and encompass a wide variety of topics, from regulatory compliance to emerging science, response and toxicity review, and molecular tumor boards.”

Source: Vivek Subbiah/Twitter

Vivek Subbiah is the Chief of Early-Phase Drug Development at the Sarah Cannon Research Institute. He is the former Executive Director of Oncology Research at the MD Anderson Cancer Network and a former Associate Professor in the Department of Investigational Cancer Therapeutics at The University of Texas MD Anderson Cancer Center. Dr. Subbiah’s research interests include drug development in rare cancers, immunotherapy, and radiopharmaceuticals.