Gertjan Rasschaert: Botbal in refractory pMMR/MSS mCRC: a phase 1 trial by Andrea J. Bullock et al.

Gertjan Rasschaert, Medical Doctor, Consultant Gastrointestinal Oncology and Gastroenterology at UZ Leuven, shared a post on LinkedIn:

“Botbal in refractory pMMR/MSS mCRC: a phase 1 trial

In the response-evaluable population (n = 101), ORR was 17% (95% CI 10–26%), DCR 61% (95% CI, 51–71%) and median PFS 3.5 months (95% CI, 2.7–4.1 months), at a median FU of 10.3 months.

A randomized phase 2 study of this combination is underway to confirm the comparative safety and efficacy of the BOT and BAL combination. With enthusiast participation of DIO UZ Leuven !

g is cooking in the age group of 20-49 years. Also the exact reason why just lowering the screening age to 45 years won’t suffice.”

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Source: Gertjan Rasschaert/X