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Dec 7, 2024, 10:47

Rational CAR design for augmented T cell function – Journal for ImmunoTherapy of Cancer

Journal for ImmunoTherapy of Cancer shared the following on X:

“New JITC article: Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function.”

Rational CAR design for augmented T cell function - Journal for ImmunoTherapy of Cancer

Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function

Authors: Markus Barden, Patrick Ronan Elsenbroich, Vivian Haas, Moritz Ertelt, Philip Pervan, Lukas Velas, Bence Gergely, Árpád Szöőr, Dennis Christoph Harrer, Valerie Bezler, Astrid Holzinger, Rasmus Ulslev Wegener Friis, Gyorgy Vereb, Gerhard J Schütz, Clara T Schoeder, Andreas A Hombach, Hinrich Abken

Rational CAR design for augmented T cell function - Journal for ImmunoTherapy of Cancer

advanced therapies cancer Cancer research cancer treatment advancements CAR design CAR-T cell engineering immune responses immunotherapy Journal for ImmunoTherapy of Cancer OncoDaily Oncology Oncology Innovation T cell function

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