Aren Karapetyan: New Insights on Treatment for Squamous Cell Carcinoma of the Anus

Aren Karapetyan, Oncology Resident at Yerevan State Medical University, shared a post on LinkedIn:

“New Insights on Treatment for Squamous Cell Carcinoma of the Anus (SCCA).

A recent study explores the use of weekly cisplatin as a chemoradiotherapy (CRT) option for SCCA, offering promising results with reduced toxicity compared to traditional regimens.

Key findings:

• Safe and effective: Weekly cisplatin showed an acceptable acute toxicity profile and good outcomes.
• Improved compliance: Lower hematological toxicity was observed compared to historical data.
• Positive outcomes: 5-year Disease-Free Survival (DFS) was 77%, with Overall Survival (OS) at 86%.
• This approach may offer a more tolerable option for patients while maintaining high treatment efficacy.”

“Feasibility of weekly cisplatin and radiotherapy for localized anal cancer – A Danish anal cancer group report”

Authors: Anne Vittrup Jakobsen, Camilla Jensenius Skovhus Kronborg, Rikke Kjer Oksen, Birgitte Mayland Havelund, Karen Lycke Wind, Karen-Lise Garm Spindler

Source: Aren Karapetyan/LinkedIn

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